A ground breaking study published on IntechOpen has reveal that Sea Buckthorn (Hippophae rhamnoides), a robust shrub native to the Himalayan region, has been recognized historically in Northern Asian and Tibetan traditional medicine for its remarkable therapeutic versatility. Recently, modern scientific research has provided substantial evidence supporting the numerous health benefits associated with this extraordinary plant.

Study Overview

Recent research, as outlined in the comprehensive review "Seabuckthorn Polyphenols: Characterization, Bioactivities and Associated Health Benefits," has identified over 190 bioactive nutrients in Sea Buckthorn berries, seeds, and leaves. Among these, polyphenols such as quercetin, kaempferol, isorhamnetin, catechins, proanthocyanidins, and phenolic acids have been extensively studied and documented. These polyphenolic compounds have exhibited powerful antioxidant, anti-inflammatory, hepatoprotective, cardioprotective, anti-obesity, anti-diabetic, and neuroprotective effects in numerous clinical and preclinical studies

Key findings include:

Rich Source of Bioactive Compounds:

• Sea Buckthorn (SB) berries, seeds, and leaves contain more than 190 bioactive compounds, including polyphenols (epicatechin, epigallocatechin, gallic acid, proanthocyanidins, chlorogenic acid) and flavonoids (quercetin, isorhamnetin, kaempferol glycosides, luteolin, myricetin).

• SB is uniquely rich in omega fatty acids (omega-3, 6, 7, and 9), vitamins (especially vitamin C), organic acids, minerals, and carotenoids.

• Potent Antioxidant and Anti-inflammatory Effects:

  • SB polyphenols exhibit strong antioxidant activity, reducing oxidative stress markers and inflammation indicators such as CRP and TNF-α.

• Cardiovascular and Metabolic Health Benefits:

  • Clinical evidence indicates significant improvements in metabolic profiles, including reductions in blood glucose, insulin resistance, triglycerides, and total cholesterol, along with an increase in beneficial HDL cholesterol.

  • SB polyphenols demonstrate antihypertensive, anti-obesity, and cardioprotective effects.

• Regenerative and Stem Cell Mobilization Properties:

  • SB polyphenols act as natural stem cell mobilizers, promoting endogenous stem cell activity. Specifically, SB extracts stimulate pancreatic regeneration in animal models of insulin-dependent diabetes, highlighting potential therapeutic applications in regenerative medicine.

About CyanthOx™

CyanthOx™ is a polyphenol-rich extract from the ancient sea buckthorn plant, including proanthocyanidins and flavonoids. Grown on the Tibetan Plateau, this unique blend is designed to dramatically reverse aging by enhancing cellular regeneration, boosting mitochondrial function, and providing superior antioxidant protection compared to traditional extracts. Ideal for combatting oxidative stress and aging, CyanthOx™ promotes overall cellular health and longevity.

About Puredia
Puredia is a global leader in the supply of organic, innovative, and clinically tested nutritional ingredients, specializing in the cultivation and development of Sea Buckthorn products. Established by Dr. Hywel Yuen, Puredia upholds rigorous international certification standards, including USDA, EU, Canada, and China Organic certifications, alongside Halal and Kosher accreditations. The company is distinguished by its robust commitment to scientific research, ensuring the highest levels of efficacy and safety in its offerings. Puredia's dedication to sustainability and social responsibility is evident in its management of organic-certified farms located on the Tibetan Plateau and its contributions to local communities, particularly in enhancing educational opportunities for children in surrounding areas.